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Title   임신과 합병된 유방암환자의 복합치료후 정상아 분만 1 예 ( Normal Fetal Outcome after Multimodal Therapy for Breast Carcinoma in the Early Second Trimester of Pregnancy )
Publicationinfo   1993 Jan; 025(05): 780-785.
Key_word   Fetal outcome, Chemotherapy and radiotherapy during pregnancy, Breast carcinoma
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Abstract   There were many papers stating that pregnancy had no deleterious effects to the management of the patients with malignant disease. But, it is well established that irradiation and cytotoxic drugs during pregnancy are associated with a significant risk of abortion and teratogenesis. These risks are concentrated in the first trimester and only minimal evidence of increaaed risk of malformation or abortion during the second or third trimester. We have experienced a normal fetal outcome from the case of a patient with an advanced, inflammatory breast cancer(stage III B) was diagnosed in the 2nd trimeter of the pregnancy. (18 weeks of gestation), who was managed by 4 times of combination chemotherapy(5-FU: 500 mg/m, Adriamycin; 500 mg/m and Cyclophospomide 500 mg/m) and radiotherapy(total dose 6000 rad) from 19 weeks through 32 weeks of pregnancy.
저 자   박윤희(Yun Hee Park),조삼현(Sam Hyun Cho),김경태(Kyung Tai Kim),황윤영(Youn Yeung Hwang),이재억(Jai Auk Lee),정파종(Pah Jong Jung)